After I saw this reviewed on a couple of other blogs, I had to grab it when I saw it in the library. I have to admit I've only read one other Piccoult (My Sister's Keeper) and really struggled with it - the story was really well written, just very confronting.
House Rules is the story of an 18 year old boy, Jacob Hunt. Jacob has Aspergers Syndrome and is obsessed with forensic science. He turns up at crime scenes and solves the crime for the police, and is obsessed with a crime show. When his tutor is found dead, his Asperger's traits like not looking people in the eye, and showing little emotion, lead to him being arrested and charged with her murder.
The story is told from the points of view of Jacob, his mum Emma, brother Theo, the policeman Rich and his lawyer Oliver. I don't know how accurate the portrayal is of someone with Aspergers - I suspect some of the characteristics were emphasised for the sake of the novel. I found it quite a compelling read, though I had to put it aside for a few days half way through as it got a bit intense.